Acetoacetyl Coenzyme A Synthetase (AACS)
SUR-5; ACSF1; Protein sur-5 homolog; Acyl-CoA synthetase family member 1
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The activity of acetoacetyl-CoA synthetase, a cytoplasmic enzyme that activates acetoacetate, was found to be highly regulated by modulators known to affect the activity of 3-hydroxy-3-methylglutaryl-CoA reductase and/or cholesterol biosynthesis in liver and adrenals of adult rats. Acetoacetyl-CoA synthetase activity was depressed by feeding cholesterol or mevalonate administration and was enhanced by the addition to the diet of mevinolin and/or cholestyramine. The activity of acetoacetyl-CoA synthetase in adrenals was enhanced by treatment of the animals with 4-aminopyrazolopyrimidine. These changes in activity of acetoacetyl-CoA synthetase were in synchrony with changes in the activities of 3-hydroxy-3-methylglutaryl-CoA synthase and 3-hydroxy-3-methylglutaryl-CoA reductase.
Organism species: Homo sapiens (Human)
- Recombinant protein RPG352Hu01 Recombinant Acetoacetyl Coenzyme A Synthetase (AACS) In Stock
- Customized Service n/a Monoclonal Antibody to Acetoacetyl Coenzyme A Synthetase (AACS) Monoclonal Antibody Customized Service Offer
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Organism species: Mus musculus (Mouse)
- Recombinant protein RPG352Mu01 Recombinant Acetoacetyl Coenzyme A Synthetase (AACS) In Stock
- Polyclonal antibody PAG352Mu01 Polyclonal Antibody to Acetoacetyl Coenzyme A Synthetase (AACS) In Stock
- Customized Service n/a CLIA Kit for Acetoacetyl Coenzyme A Synthetase (AACS) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Acetoacetyl Coenzyme A Synthetase (AACS) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Acetoacetyl Coenzyme A Synthetase (AACS) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Acetoacetyl Coenzyme A Synthetase (AACS) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Acetoacetyl Coenzyme A Synthetase (AACS) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Acetoacetyl Coenzyme A Synthetase (AACS) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Acetoacetyl Coenzyme A Synthetase (AACS) ELISA Kit Customized Service Offer