Activin A Receptor Type I C (ACVR1C)
ACVR1-C; ALK7; ACVRLK7; Activin receptor-like kinase 7
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ACVR1C ACVR1C is a type I receptor for the TGFB family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors.
Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
Organism species: Homo sapiens (Human)
- Recombinant protein RPC116Hu01 Recombinant Activin A Receptor Type I C (ACVR1C) In Stock
- Polyclonal antibody PAC116Hu01 Polyclonal Antibody to Activin A Receptor Type I C (ACVR1C) In Stock
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Organism species: Mus musculus (Mouse)
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Organism species: Rattus norvegicus (Rat)
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