Adrenocorticotropic Hormone Receptor (ACTHR)

The ACTH receptor is a type of melanocortin receptor (type 2), properly known as MC₂, which is specific for ACTH.the ACTHR gene is expressed in normal corporal skin, scalp tissue, compound nevus tissue, basal cell carcinoma tissue, and cultured melanocytes; the CYP11A1 gene is expressed in squamous cell carcinoma tissue, normal facial skin, normal corporal skin, cultured melanocytes, and basal cell carcinoma tissue; the CYP17 gene is expressed in normal facial skin, corporal skin, cultured melanocytes, squamous cell carcinoma cells, and basal cell carcinoma cells; the CYP21A2 gene is expressed in melanoma tissue, squamous cell carcinoma tissue, basal cell carcinoma tissue, normal facial skin, and cultured melanocytes.