B-Cell Translocation Gene 2 (BTG2)
PC3; TIS21; BTG Family Member 2; NGF-Inducible Anti-Proliferative Protein PC3; NGF-Inducible Protein TIS21; Pheochromacytoma Cell-3
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The protein BTG2 is the human homolog of the PC3 protein in rat and of the Tis21 protein in mouse.Tis21 had been originally isolated as a sequence induced by TPA in mouse fibroblasts, whereas PC3 was originally isolated as sequence induced at the beginning of neuron differentiation; BTG2 was then isolated in human cells as sequence induced by p53 and DNA damage.
BTG2 is a member of the BTG/Tob family . This family has structurally related proteins that appear to have antiproliferative properties. In particular, the BTG2 protein has been shown to negatively control a cell cycle checkpoint at the G1 to S phase transition in fibroblasts and neuronal cells by direct inhibition of the activity of cyclin D1 promoter.
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
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Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant B-Cell Translocation Gene 2 (BTG2) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to B-Cell Translocation Gene 2 (BTG2) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to B-Cell Translocation Gene 2 (BTG2) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for B-Cell Translocation Gene 2 (BTG2) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for B-Cell Translocation Gene 2 (BTG2) ELISA Kit Customized Service Offer