B-Raf Proto Oncogene Serine/Threonine Protein Kinase (BRAF)
B-raf 1; BRAF1; RAFB1; V-Raf Murine Sarcoma Viral Oncogene Homolog B1
The B-RAF protein is involved in sending signals in cells and in cell growth. The BRAF gene may be mutated,and the B-RAF protein altered, as an inherited mutation which causes birth defects, or as an acquired mutation (oncogene) in adults which causes cancer. Drugs that treat those cancers by inhibiting B-RAF are being studied, and one, PLX4032, has started phase III clinical trials. This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase / ERKs signaling pathway, which affects cell division, differentiation, and secretion.Mutations in the BRAF gene can cause disease in two ways. First, mutations can be inherited and cause birth defects. Second, mutations can appear later in life and cause cancer, as an oncogene.
Organism species: Homo sapiens (Human)
- Recombinant protein RPG347Hu01 Recombinant B-Raf Proto Oncogene Serine/Threonine Protein Kinase (BRAF) In Stock
- Conjugated small molecules CPG347Hu11 BSA Conjugated B-Raf Proto Oncogene Serine/Threonine Protein Kinase (BRAF) In Stock
- Conjugated small molecules CPG347Hu12 BSA Conjugated B-Raf Proto Oncogene Serine/Threonine Protein Kinase (BRAF) In Stock
- Monoclonal antibody MAG347Hu21 Monoclonal Antibody to B-Raf Proto Oncogene Serine/Threonine Protein Kinase (BRAF) In Stock
- Polyclonal antibody PAG347Hu01 Polyclonal Antibody to B-Raf Proto Oncogene Serine/Threonine Protein Kinase (BRAF) In Stock
- Sandwich ELISA SEG347Hu ELISA Kit for B-Raf Proto Oncogene Serine/Threonine Protein Kinase (BRAF) In Stock
Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant B-Raf Proto Oncogene Serine/Threonine Protein Kinase (BRAF) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to B-Raf Proto Oncogene Serine/Threonine Protein Kinase (BRAF) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to B-Raf Proto Oncogene Serine/Threonine Protein Kinase (BRAF) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for B-Raf Proto Oncogene Serine/Threonine Protein Kinase (BRAF) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for B-Raf Proto Oncogene Serine/Threonine Protein Kinase (BRAF) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant B-Raf Proto Oncogene Serine/Threonine Protein Kinase (BRAF) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to B-Raf Proto Oncogene Serine/Threonine Protein Kinase (BRAF) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to B-Raf Proto Oncogene Serine/Threonine Protein Kinase (BRAF) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for B-Raf Proto Oncogene Serine/Threonine Protein Kinase (BRAF) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for B-Raf Proto Oncogene Serine/Threonine Protein Kinase (BRAF) ELISA Kit Customized Service Offer