B-Cell CLL/Lymphoma 10 (Bcl10)
CARMEN; CIPER; CLAP; c-E10; mE10; CARD-containing molecule enhancing NF-kappa-B; CED-3/ICH-1 prodomain homologous E10-like regulator; Cellular homolog of vCARMEN
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This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. B-cell lymphoma/leukemia 10 contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.
Organism species: Homo sapiens (Human)
- Recombinant protein RPC326Hu01 Recombinant B-Cell CLL/Lymphoma 10 (Bcl10) In Stock
- Polyclonal antibody PAC326Hu01 Polyclonal Antibody to B-Cell CLL/Lymphoma 10 (Bcl10) In Stock
- Customized Service n/a CLIA Kit for B-Cell CLL/Lymphoma 10 (Bcl10) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for B-Cell CLL/Lymphoma 10 (Bcl10) ELISA Kit Customized Service Offer
Organism species: Mus musculus (Mouse)
- Recombinant protein RPC326Mu01 Recombinant B-Cell CLL/Lymphoma 10 (Bcl10) In Stock
- Polyclonal antibody PAC326Mu01 Polyclonal Antibody to B-Cell CLL/Lymphoma 10 (Bcl10) In Stock
- Customized Service n/a CLIA Kit for B-Cell CLL/Lymphoma 10 (Bcl10) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for B-Cell CLL/Lymphoma 10 (Bcl10) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant B-Cell CLL/Lymphoma 10 (Bcl10) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to B-Cell CLL/Lymphoma 10 (Bcl10) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to B-Cell CLL/Lymphoma 10 (Bcl10) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for B-Cell CLL/Lymphoma 10 (Bcl10) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for B-Cell CLL/Lymphoma 10 (Bcl10) ELISA Kit Customized Service Offer