BT-474 Breast Ductal Carcinoma Cells (BT-474)

The BT474 cell line is a widely studied human breast cancer cell line that was originally derived from a ductal carcinoma in situ (DCIS) lesion in the breast of a 56-year-old patient. BT474 cells are known for their luminal-like characteristics and high expression of the estrogen receptor (ER) and human epidermal growth factor receptor 2 (HER2). These receptors play crucial roles in breast cancer development and progression, making the BT474 cell line a valuable model for studying hormone-dependent and HER2-positive breast cancers.

BT474 cell line serves as a valuable tool for studying hormone-dependent and HER2-positive breast cancers, providing insights into the underlying mechanisms of tumor growth, progression, and response to therapy. Its unique characteristics make BT474 cells a versatile model for preclinical research, drug screening, and the development of personalized treatment strategies for patients with breast cancer.