Butyrylcholinesterase (BCHE)
BuChE; CHE1; E1; Pseudocholinesterase; Cholinesterase; Acylcholine acylhydrolase; Butyrylcholine esterase; Choline esterase II
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Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. Butyrylcholinesterase is believed to play a role in the body's ability to metabolize the drug cocaine. In 2008, an experimental new drug was discovered for the potential treatment of cocaine abuse and overdose based on the BChE structure. It was shown to remove cocaine from the body 2000 times as fast as the natural form of BChE. Studies in rats have shown that the drug prevented convulsions and death when administered cocaine overdoses.
Organism species: Homo sapiens (Human)
- Recombinant protein RPC348Hu01 Recombinant Butyrylcholinesterase (BCHE) In Stock
- Recombinant protein RPC348Hu02 Recombinant Butyrylcholinesterase (BCHE) In Stock
- Polyclonal antibody PAC348Hu01 Polyclonal Antibody to Butyrylcholinesterase (BCHE) In Stock
- Monoclonal antibody MAC348Hu22 Monoclonal Antibody to Butyrylcholinesterase (BCHE) In Stock
- Polyclonal antibody PAC348Hu02 Polyclonal Antibody to Butyrylcholinesterase (BCHE) In Stock
- Sandwich ELISA SEC348Hu ELISA Kit for Butyrylcholinesterase (BCHE) In Stock
Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant Butyrylcholinesterase (BCHE) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Butyrylcholinesterase (BCHE) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Butyrylcholinesterase (BCHE) Polyclonal Antibody Customized Service Offer
- Competition ELISA CEC348Mu ELISA Kit for Butyrylcholinesterase (BCHE) In Stock
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPC348Ra01 Recombinant Butyrylcholinesterase (BCHE) In Stock
- Polyclonal antibody PAC348Ra01 Polyclonal Antibody to Butyrylcholinesterase (BCHE) In Stock
- Monoclonal antibody MAC348Ra21 Monoclonal Antibody to Butyrylcholinesterase (BCHE) In Stock
- Sandwich ELISA SEC348Ra ELISA Kit for Butyrylcholinesterase (BCHE) In Stock
- Competition ELISA CEC348Ra ELISA Kit for Butyrylcholinesterase (BCHE) In Stock