CD200 Receptor 1 (CD200R1)
OX2R; HCRTR2; CD200R; MOX2R; MOX2 Receptor; Cell surface glycoprotein CD200 receptor 1; CD200 cell surface glycoprotein receptor; Cell surface glycoprotein OX2 receptor 1
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CD200R1 encodes a receptor for the OX-2 membrane glycoprotein. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. Alternative splicing of this gene results in multiple transcript variants. CD200R was expressed on human and murine mast cells. Engagement of CD200R by CD200 resulted in potent inhibition of mast cell degranulation and cytokine secretion.CD200R does not contain an immunoreceptor tyrosine-based inhibitory motif (ITIM) and thus represents a novel receptor that can be targeted in vivo to regulate mast cell-dependent pathologies.
Organism species: Homo sapiens (Human)
- Recombinant protein RPN341Hu01 Recombinant CD200 Receptor 1 (CD200R1) In Stock
- Polyclonal antibody PAN341Hu01 Polyclonal Antibody to CD200 Receptor 1 (CD200R1) In Stock
- Monoclonal antibody MAN341Hu21 Monoclonal Antibody to CD200 Receptor 1 (CD200R1) In Stock
- Sandwich ELISA SEN341Hu ELISA Kit for CD200 Receptor 1 (CD200R1) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPN341Mu01 Recombinant CD200 Receptor 1 (CD200R1) In Stock
- Polyclonal antibody PAN341Mu01 Polyclonal Antibody to CD200 Receptor 1 (CD200R1) In Stock
- Customized Service n/a CLIA Kit for CD200 Receptor 1 (CD200R1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for CD200 Receptor 1 (CD200R1) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant CD200 Receptor 1 (CD200R1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to CD200 Receptor 1 (CD200R1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to CD200 Receptor 1 (CD200R1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for CD200 Receptor 1 (CD200R1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for CD200 Receptor 1 (CD200R1) ELISA Kit Customized Service Offer