Calpain, Small Subunit 1 (CAPNS1)
CANP; 30K; Calpain 4; CANPS; CAPN4; CDPS; Calcium-activated neutral proteinase small subunit; Calcium-dependent protease small subunit; Calpain regulatory subunit
Calpain small subunit 1 is a protein encoded by the CAPNS1 gene.Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.Regulatory subunit of the calcium-regulated non- lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
Organism species: Homo sapiens (Human)
- Recombinant protein RPF258Hu01 Recombinant Calpain, Small Subunit 1 (CAPNS1) In Stock
- Monoclonal antibody MAF258Hu21 Monoclonal Antibody to Calpain, Small Subunit 1 (CAPNS1) In Stock
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- Sandwich ELISA SEF258Hu ELISA Kit for Calpain, Small Subunit 1 (CAPNS1) In Stock
Organism species: Mus musculus (Mouse)
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- Sandwich ELISA SEF258Mu ELISA Kit for Calpain, Small Subunit 1 (CAPNS1) In Stock
Organism species: Rattus norvegicus (Rat)
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- Sandwich ELISA SEF258Ra ELISA Kit for Calpain, Small Subunit 1 (CAPNS1) In Stock