Cardiotrophin Like Cytokine Factor 1 (CLCF1)
CLC; NR6; BSF3; CISS2; NNT1; Novel Neurotrophin-1; B Cell-Stimulating Factor-3
-92389.jpg)
IL6 family members share similarity in gene structure and have a 4-helix bundle in their protein structure. CLCF1 is closely related to other proteins called cardiotrophin-1 and ciliary neurotrophic factor.
CLCF1 induces tyrosine phosphorylation of the IL-6 receptor common subunit glycoprotein 130 (gp130), leukemia inhibitory factor receptor beta, and the transcription factor STAT3. It has been implicated in the induction of IL-1 (via induction of corticosterone and IL-6) and serum amyloid A, and in B cell hyperplasia. This cytokine is capable of B cell activation via gp130 receptor stimulation.The term "neurotrophin" is commonly used to refer collectively to the four structurally related factors NGF, BDNF, NT-3 and NT-4, while NNT1 bears no structural resemblance to these four proteins.
Organism species: Homo sapiens (Human)
- Recombinant protein RPC389Hu01 Recombinant Cardiotrophin Like Cytokine Factor 1 (CLCF1) In Stock
- Polyclonal antibody PAC389Hu01 Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) In Stock
- Monoclonal antibody MAC389Hu22 Monoclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) In Stock
- Labelled antibody LAC389Hu71 Biotin-Linked Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) In Stock
- Sandwich ELISA SEC389Hu ELISA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) In Stock
- Sandwich CLIA SCC389Hu CLIA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPC389Mu01 Recombinant Cardiotrophin Like Cytokine Factor 1 (CLCF1) In Stock
- Recombinant protein RPC389Mu02 Recombinant Cardiotrophin Like Cytokine Factor 1 (CLCF1) In Stock
- Polyclonal antibody PAC389Mu01 Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) In Stock
- Polyclonal antibody PAC389Mu02 Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) In Stock
- Sandwich ELISA SEC389Mu ELISA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) In Stock
- Sandwich CLIA SCC389Mu CLIA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) In Stock
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPC389Ra01 Recombinant Cardiotrophin Like Cytokine Factor 1 (CLCF1) In Stock
- Polyclonal antibody PAC389Ra01 Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) In Stock
- Monoclonal antibody MAC389Ra21 Monoclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) In Stock
- Sandwich ELISA SEC389Ra ELISA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) In Stock
- Sandwich CLIA SCC389Ra CLIA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) In Stock