Coiled Coil Domain Containing Protein 114 (CCDC114)

Coiled-coil domain-containing protein 114 is a protein encoded by the CCDC114 gene. A coiled coil is a structural motif in proteins, in which 2-7 alpha-helices are coiled together like the strands of a rope (Dimers and trimers are the most common types).
The coiled coil is a common structural motif, formed by approximately 3 ± 5% of all amino acids in proteins. Typically, it consists of two to five -helices wrapped around each other into a left-handed helix to form a supercoil. Whereas regular-helices go through 3.6 residues for each complete turn of the helix, the distortion imposed upon each helix within a left-handed coiled coil lowers this value to around 3.5. Thus a heptad repeat occurs every two turns of the helix.