Coiled Coil Domain Containing Protein 138 (CCDC138)

The CCDC138 protein is predated to have a molecular weight of 76.2Kda[6] and an isoelectric point of 8.614.Compositional analysis shows that there is a low usage of the AGP grouping in CCDC138, and there are no positive, negative or mixed charge clusters. The protein has no ER retention motif in the C-terminus and no RNA binding motif. It has also been predicted to be a soluble nuclear protein with a leucine zipper pattern at position 205 onwards with a sequence LQKRERFLLEREQLLFRHENAL. A domain of unknown function on the protein at location 212 - 315 has been characterized in bacteria. TMHMM and TMAP suggests that there are no predicted transmembrane domain. SOSUI further predicts that CCDC138 is a soluble protein with no transmembrane domain.