Collagen Type VI Alpha 3 (COL6a3)
COL6-A3; Collagen Alpha-3(VI)chain
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Collagen alpha-3(VI) chain is one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The alpha 3 chain of type VI collagen is much larger than the alpha 1 and 2 chains.
This difference in size is largely due to an increase in the number of subdomains, similar to von Willebrand Factor type A domains, found in the amino terminal globular domain of all the alpha chains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in the type VI collagen genes are associated with Bethlem myopathy. In addition to the full length transcript, four transcript variants have been identified that encode proteins with N-terminal globular domains of varying sizes.
Organism species: Homo sapiens (Human)
- Recombinant protein RPC148Hu01 Recombinant Collagen Type VI Alpha 3 (COL6a3) In Stock
- Polyclonal antibody PAC148Hu01 Polyclonal Antibody to Collagen Type VI Alpha 3 (COL6a3) In Stock
- Monoclonal antibody MAC148Hu22 Monoclonal Antibody to Collagen Type VI Alpha 3 (COL6a3) In Stock
- Sandwich ELISA SEC148Hu ELISA Kit for Collagen Type VI Alpha 3 (COL6a3) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPC148Mu01 Recombinant Collagen Type VI Alpha 3 (COL6a3) In Stock
- Polyclonal antibody PAC148Mu01 Polyclonal Antibody to Collagen Type VI Alpha 3 (COL6a3) In Stock
- Customized Service n/a CLIA Kit for Collagen Type VI Alpha 3 (COL6a3) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Collagen Type VI Alpha 3 (COL6a3) ELISA Kit Customized Service Offer