Collagen Type XVII (COL17)
COL17A1; BP180; BPAG2; LAD-1; LABD97; Collagen Alpha-1(XVII)chain; 180 kDa bullous pemphigoid antigen 2; Bullous pemphigoid antigen 2; Linear IgA disease antigen 1
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Collagen XVII, previously called BP180, is a transmembrane protein which plays a critical role in maintaining the linkage between the intracellular and the extracellular structural elements involved in epidermal adhesion .Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form.
Organism species: Homo sapiens (Human)
- Recombinant protein RPC135Hu01 Recombinant Collagen Type XVII (COL17) In Stock
- Polyclonal antibody PAC135Hu01 Polyclonal Antibody to Collagen Type XVII (COL17) In Stock
- Monoclonal antibody MAC135Hu22 Monoclonal Antibody to Collagen Type XVII (COL17) In Stock
- Labelled antibody LAC135Hu71 Biotin-Linked Polyclonal Antibody to Collagen Type XVII (COL17) In Stock
- Sandwich ELISA SEC135Hu ELISA Kit for Collagen Type XVII (COL17) In Stock
Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant Collagen Type XVII (COL17) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Collagen Type XVII (COL17) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Collagen Type XVII (COL17) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Collagen Type XVII (COL17) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Collagen Type XVII (COL17) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Collagen Type XVII (COL17) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Collagen Type XVII (COL17) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Collagen Type XVII (COL17) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Collagen Type XVII (COL17) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Collagen Type XVII (COL17) ELISA Kit Customized Service Offer