Cryptochrome 1 (CRY1)

CRY proteins belong to a superfamily of flavoproteins that occurs in all kingdoms of life. The structure has a fold very similar to photolyase, with a single molecule of FAD noncovalently bound to the protein. These proteins have variable lengths and surfaces on the C-terminal end when compared to one another, due to the lack of DNA repair enzymes which ultimately results in changes in genome and appearance. The Ramachandran plot, shows that the secondary structure of the CRY1 protein is primarily in a right-handed alpha helix conformation with little to no steric overlap.The structure of CRY1 is almost entirely made up of alpha helicies, with remaining portions in loops and has few beta sheets present in the molecule. The molecule is arranged as an orthogonal bundle.