Deoxythymidylate Kinase (DTYMK)
CDC8; TMPK; TYMK; Thymidylate Kinase; dTMP Kinase
Thymidylate kinase (EC 2.7.4.9; ATP:dTMP phosphotransferase) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. Knowledge of the essential function of dTMP kinase in eukaryotes comes from the study of a cell cycle mutant, cdc8, in Saccharomyces cerevisiae. The product of the cdc8 gene is involved in the elongation step of S phase in cell cycle progression. Huang et al. (1994) cloned the human thymidylate kinase gene by complementation with the cdc8 mutation. The cDNA sequence revealed an open reading frame that encodes a protein with a molecular weight of 23,806. Structural and functional analyses suggested that the cDNA codes for authentic human dTMP kinase. The mRNA levels and enzyme activities corresponded to cell cycle progression and cell growth stages.
Organism species: Homo sapiens (Human)
- Recombinant protein RPD780Hu01 Recombinant Deoxythymidylate Kinase (DTYMK) In Stock
- Polyclonal antibody PAD780Hu01 Polyclonal Antibody to Deoxythymidylate Kinase (DTYMK) In Stock
- Customized Service n/a CLIA Kit for Deoxythymidylate Kinase (DTYMK) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Deoxythymidylate Kinase (DTYMK) ELISA Kit Customized Service Offer
Organism species: Mus musculus (Mouse)
- Recombinant protein RPD780Mu01 Recombinant Deoxythymidylate Kinase (DTYMK) In Stock
- Polyclonal antibody PAD780Mu01 Polyclonal Antibody to Deoxythymidylate Kinase (DTYMK) In Stock
- Monoclonal antibody MAD780Mu21 Monoclonal Antibody to Deoxythymidylate Kinase (DTYMK) In Stock
- Monoclonal antibody MAD780Mu22 Monoclonal Antibody to Deoxythymidylate Kinase (DTYMK) In Stock
- Monoclonal antibody MAD780Mu23 Monoclonal Antibody to Deoxythymidylate Kinase (DTYMK) In Stock
- Monoclonal antibody MAD780Mu24 Monoclonal Antibody to Deoxythymidylate Kinase (DTYMK) In Stock
- Monoclonal antibody MAD780Mu25 Monoclonal Antibody to Deoxythymidylate Kinase (DTYMK) In Stock
- Monoclonal antibody MAD780Mu27 Monoclonal Antibody to Deoxythymidylate Kinase (DTYMK) In Stock
- Monoclonal antibody MAD780Mu29 Monoclonal Antibody to Deoxythymidylate Kinase (DTYMK) In Stock
- Customized Service n/a CLIA Kit for Deoxythymidylate Kinase (DTYMK) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Deoxythymidylate Kinase (DTYMK) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPD780Ra01 Recombinant Deoxythymidylate Kinase (DTYMK) In Stock
- Polyclonal antibody PAD780Ra01 Polyclonal Antibody to Deoxythymidylate Kinase (DTYMK) In Stock
- Customized Service n/a CLIA Kit for Deoxythymidylate Kinase (DTYMK) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Deoxythymidylate Kinase (DTYMK) ELISA Kit Customized Service Offer