Dermal Lymphatic Endothelial Cells (DLEC)

The lymphatic system is an essential part of the immune system. It serves distinct yet complementary functions with the blood vascular system in maintaining tissue homeostasis, including interstitial protein transport, tissue fluid balance, pressure equilibrium, and development of cellular immunity. Although lymphatic capillary endothelial cells have many properties in common with the endothelium of blood vessels, they possess distinct structural characteristics reflecting specific functions.

Dermal lymphatic endothelial cells(DLEC) are isolated from skin tissue, which is the main structure of the lymphatic vessel wall, and participate in the process of maintaining the balance of body fluid, regulating the recycling of lymphocytes and the immune response of the body.