Endometrial Epithelial Cells (EEC)

Endometrium is a layer of the inner wall of a mammal. The endometrium is covered with mucous membrane, which is composed of the mucosa epithelium and the underlying layer. The lower part of the mucosal epithelium is called the functional layer, which forms the uterine gland and responds to the estrogen. The lower layer of the functional layer is called the basal layer, which is rich in blood vessels.

Endometrial epithelial cells (EEC) are in a single lamellar arrangement, the shape of tadpoles, clear cell outline, the nucleus is large and obvious. There are small filamentous connections between cells, and often around a small group of cells. The cells were positive for cytokeratin, vimentin positive cells rarely. Endometrial epithelial cells provide an ideal and valuable experimental model for the study of the pathogenesis of uterine diseases or therapeutic drug screening.