Eukaryotic Translation Elongation Factor 1 Beta 2 (EEF1b2)
EEF1B1; EF1B; EEF1B
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EEF1b2 encodes a translation elongation factor. The protein is a guanine nucleotide exchange factor involved in the transfer of aminoacylated tRNAs to the ribosome. Alternative splicing results in three transcript variants which differ only in the 5' UTR. Eukaryotic elongation factor-1 consists of 4 subunits, EF1-alpha, EF1-beta, EF1-gamma, and EF1-delta. EIF-alpha-GTP transfers aminoacyl-tRNA to the ribosome, and the release of animoacyl-tRNA from EIF-alpha-GTP is driven by GTP hydrolysis. EF1-alpha-GDP is recycled to EF1-alpha-GTP by the EF1-beta, -gamma, and -delta subunits.EF1-beta, -gamma, and -delta showed a perinuclear distribution and colocalized with an endoplasmic reticulum resident protein in human foreskin fibroblasts. In contrast, EF1-alpha showed strong nuclear staining and diffuse cytoplasmic staining.
Organism species: Homo sapiens (Human)
- Recombinant protein RPF022Hu01 Recombinant Eukaryotic Translation Elongation Factor 1 Beta 2 (EEF1b2) In Stock
- Polyclonal antibody PAF022Hu01 Polyclonal Antibody to Eukaryotic Translation Elongation Factor 1 Beta 2 (EEF1b2) In Stock
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Organism species: Mus musculus (Mouse)
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Organism species: Rattus norvegicus (Rat)
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- Customized Service n/a Polyclonal Antibody to Eukaryotic Translation Elongation Factor 1 Beta 2 (EEF1b2) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Eukaryotic Translation Elongation Factor 1 Beta 2 (EEF1b2) CLIA Kit Customized Service Offer
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