Eukaryotic Translation Initiation Factor 4A1 (EIF4A1)
DDX2A; EIF-4A; EIF4A; ATP-dependent RNA helicase eIF4A-1
The eukaryotic initiation factor-4A family consists of 2 closely related genes, EIF4A1 and EIF4A2. These factors are required for the binding of mRNA to 40S ribosomal subunits. Nielsen et al. (1985) cloned eif4a1 cDNAs from mouse liver. They identified 2 distinct cDNAs differing in their untranslated regions. The sizes of these cDNAs correspond to 2 discrete mRNA bands of 2.0 and 1.6 kb seen on Northern blots of both mouse and human cells. Nielsen and Trachsel (1988) found that eif4a1 was expressed at similar levels in all mouse tissues examined, while eif4a2 had a much more varied pattern of expression. The EIF4A1 cDNA encodes a predicted 406-amino acid polypeptide with 92.7% amino acid similarity to the mouse protein. Kukimoto et al. (1997) characterized the promoter region of human EIF4A1.
Organism species: Homo sapiens (Human)
- Recombinant protein RPF009Hu01 Recombinant Eukaryotic Translation Initiation Factor 4A1 (EIF4A1) In Stock
- Polyclonal antibody PAF009Hu01 Polyclonal Antibody to Eukaryotic Translation Initiation Factor 4A1 (EIF4A1) In Stock
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Organism species: Mus musculus (Mouse)
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Organism species: Rattus norvegicus (Rat)
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- Customized Service n/a CLIA Kit for Eukaryotic Translation Initiation Factor 4A1 (EIF4A1) CLIA Kit Customized Service Offer
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