Fc Fragment Of IgG Low Affinity IIb, Receptor (FcgR2B)
CD32; FCG2; FCGR2; IGFR2; Low affinity immunoglobulin gamma Fc region receptor II-b
-84061.jpg)
FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.Sequence analysis predicted that the 291-amino acid protein has a 42-residue signal sequence; 2 extracellular Ig-like domains with 3 potential N-glycosylation sites; a transmembrane region; and a 43-amino acid cytoplasmic region. Immunofluorescence microscopy demonstrated surface expression of FCGR2B, and prolonged incubation with ligand led to endocytosis.
Organism species: Homo sapiens (Human)
- Recombinant protein RPQ061Hu01 Recombinant Fc Fragment Of IgG Low Affinity IIb, Receptor (FcgR2B) In Stock
- Polyclonal antibody PAQ061Hu01 Polyclonal Antibody to Fc Fragment Of IgG Low Affinity IIb, Receptor (FcgR2B) In Stock
- Sandwich ELISA SEQ061Hu ELISA Kit for Fc Fragment Of IgG Low Affinity IIb, Receptor (FcgR2B) In Stock
Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant Fc Fragment Of IgG Low Affinity IIb, Receptor (FcgR2B) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Fc Fragment Of IgG Low Affinity IIb, Receptor (FcgR2B) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Fc Fragment Of IgG Low Affinity IIb, Receptor (FcgR2B) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Fc Fragment Of IgG Low Affinity IIb, Receptor (FcgR2B) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Fc Fragment Of IgG Low Affinity IIb, Receptor (FcgR2B) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Fc Fragment Of IgG Low Affinity IIb, Receptor (FcgR2B) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Fc Fragment Of IgG Low Affinity IIb, Receptor (FcgR2B) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Fc Fragment Of IgG Low Affinity IIb, Receptor (FcgR2B) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Fc Fragment Of IgG Low Affinity IIb, Receptor (FcgR2B) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Fc Fragment Of IgG Low Affinity IIb, Receptor (FcgR2B) ELISA Kit Customized Service Offer