Fibroblast Activation Protein Alpha (FAPa)
APCE; SIMP; DPPIV; Seprase; 170 kDa melanoma membrane-bound gelatinase; Post-proline cleaving enzyme; Serine integral membrane protease; Surface-expressed protease
Fibroblast activation protein, alpha, also known as FAP, is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. FAP, also known as seprase, belongs to the clan SC proteases and is a member of the S9B prolyl oligopeptidase subfamily. Other members of the S9B subfamily are DPPIV, DPP8 and DPP9. FAP is most closely related to DPPIV and they share about 50% of there amino acids.
Organism species: Homo sapiens (Human)
- Recombinant protein RPC469Hu01 Recombinant Fibroblast Activation Protein Alpha (FAPa) In Stock
- Polyclonal antibody PAC469Hu01 Polyclonal Antibody to Fibroblast Activation Protein Alpha (FAPa) In Stock
- Monoclonal antibody MAC469Hu22 Monoclonal Antibody to Fibroblast Activation Protein Alpha (FAPa) In Stock
- Monoclonal antibody MAC469Hu21 Monoclonal Antibody to Fibroblast Activation Protein Alpha (FAPa) In Stock
- Monoclonal antibody MAC469Hu23 Monoclonal Antibody to Fibroblast Activation Protein Alpha (FAPa) In Stock
- Monoclonal antibody MAC469Hu24 Monoclonal Antibody to Fibroblast Activation Protein Alpha (FAPa) In Stock
- Monoclonal antibody MAC469Hu25 Monoclonal Antibody to Fibroblast Activation Protein Alpha (FAPa) In Stock
- Sandwich ELISA SEC469Hu ELISA Kit for Fibroblast Activation Protein Alpha (FAPa) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPC469Mu01 Recombinant Fibroblast Activation Protein Alpha (FAPa) In Stock
- Recombinant protein RPC469Mu02 Recombinant Fibroblast Activation Protein Alpha (FAPa) In Stock
- Polyclonal antibody PAC469Mu01 Polyclonal Antibody to Fibroblast Activation Protein Alpha (FAPa) In Stock
- Polyclonal antibody PAC469Mu02 Polyclonal Antibody to Fibroblast Activation Protein Alpha (FAPa) In Stock
- Sandwich ELISA SEC469Mu ELISA Kit for Fibroblast Activation Protein Alpha (FAPa) In Stock
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPC469Ra01 Recombinant Fibroblast Activation Protein Alpha (FAPa) In Stock
- Polyclonal antibody PAC469Ra01 Polyclonal Antibody to Fibroblast Activation Protein Alpha (FAPa) In Stock
- Monoclonal antibody MAC469Ra21 Monoclonal Antibody to Fibroblast Activation Protein Alpha (FAPa) In Stock
- Sandwich ELISA SEC469Ra ELISA Kit for Fibroblast Activation Protein Alpha (FAPa) In Stock