Gastric Smooth Muscle Cells (GSMC)

Smooth muscle is responsible for the contraction of hollow organs, such as blood vessels, gastrointestinal tract, bladder and uterus and other organs. Smooth muscle cells are connected to each other, to form a tubular structure or a hollow organ; they can produce continuous contraction or tonic contraction, make organs against the load while maintaining the original shape. Smooth muscle contraction  is the key to the contraction of gastrointestinal motility, may be through the activation of phospholipase elevated intracellular Ca2 + concentration, activate G proteins and PKC zeta activation mechanism to complete. In vitro studies also showed that gastric smooth muscle cells express the endothelin and endothelial nitric oxide synthase. Gastric smooth muscle cells are taken from gastric tissue.