Heat Shock Transcription Factor 1 (HSF1)
HSTF1; Heat shock factor protein 1
Heat shock proteins (HSP) are a group of proteins whose expression is increased when the cells are exposed to elevated temperatures or other stress. It was discovered that Heat Shock Factor 1(HSF1) is a powerful multifaceted modifier of carcinogenesis. HSF1 knockout mice show significantly decreased incidence of skin tumor after topical application of DMBA, a mutagen .HSF1 is potent and activated rapidly though transiently by heat shock, whereas HSF2 is a less active transcriptional regulator but can retain its DNA binding properties for extended periods. In vertebrates, HSF1 mediates the ubiquitous response to stress stimuli, while the role of a second HSE-binding factor, HSF2, is still unclear. HSF2 shows common structural domains with HSF1; however, it is active at normal temperatures.
Organism species: Homo sapiens (Human)
- Recombinant protein RPA435Hu01 Recombinant Heat Shock Transcription Factor 1 (HSF1) In Stock
- Polyclonal antibody PAA435Hu01 Polyclonal Antibody to Heat Shock Transcription Factor 1 (HSF1) In Stock
- Monoclonal antibody MAA435Hu22 Monoclonal Antibody to Heat Shock Transcription Factor 1 (HSF1) In Stock
- Sandwich ELISA SEA435Hu ELISA Kit for Heat Shock Transcription Factor 1 (HSF1) In Stock
Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant Heat Shock Transcription Factor 1 (HSF1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Heat Shock Transcription Factor 1 (HSF1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Heat Shock Transcription Factor 1 (HSF1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Heat Shock Transcription Factor 1 (HSF1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Heat Shock Transcription Factor 1 (HSF1) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPA435Ra01 Recombinant Heat Shock Transcription Factor 1 (HSF1) In Stock
- Polyclonal antibody PAA435Ra01 Polyclonal Antibody to Heat Shock Transcription Factor 1 (HSF1) In Stock
- Monoclonal antibody MAA435Ra21 Monoclonal Antibody to Heat Shock Transcription Factor 1 (HSF1) In Stock
- Sandwich ELISA SEA435Ra ELISA Kit for Heat Shock Transcription Factor 1 (HSF1) In Stock