Hemopoietic Cell Kinase (HCK)
JTK9; Hematopoietic cell kinase; p59-HCK/p60-HCK
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Tyrosine-protein kinase HCK is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization.HCK, the deduced amino acid sequence of the protein encoded by HCK, and the distribution of RNA transcribed from HCK among various hemopoietic cells.Since this region is affected by interstitial deletions in some acute myeloid leukemias and myeloproliferative disorders, they suggested that damage to HCK may contribute to the pathogenesis of these conditions.
Organism species: Homo sapiens (Human)
- Recombinant protein RPC522Hu01 Recombinant Hemopoietic Cell Kinase (HCK) In Stock
- Polyclonal antibody PAC522Hu01 Polyclonal Antibody to Hemopoietic Cell Kinase (HCK) In Stock
- Sandwich ELISA SEC522Hu ELISA Kit for Hemopoietic Cell Kinase (HCK) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPC522Mu01 Recombinant Hemopoietic Cell Kinase (HCK) In Stock
- Polyclonal antibody PAC522Mu01 Polyclonal Antibody to Hemopoietic Cell Kinase (HCK) In Stock
- Customized Service n/a CLIA Kit for Hemopoietic Cell Kinase (HCK) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Hemopoietic Cell Kinase (HCK) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Hemopoietic Cell Kinase (HCK) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Hemopoietic Cell Kinase (HCK) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Hemopoietic Cell Kinase (HCK) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Hemopoietic Cell Kinase (HCK) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Hemopoietic Cell Kinase (HCK) ELISA Kit Customized Service Offer