Hepatic Stellate Cells (HSC)
Hepatic stellate cells ( HSC), also known as perisinusoidal cells or Ito cells , are pericytes found in the perisinusoidal spaceof the liver also known as the space of Disse. The stellate cell is the major cell type involved in liver fibrosis, which is the formation of scar tissue in response to liver damage.In normal liver, stellate cells are described as being in a quiescent state. When the liver is damaged, stellate cells can change into an activated state. The activated stellate cell is characterized by proliferation, contractility, and chemotaxis. The senescent hepatic stellate cells have been demonstrated to limit liver fibrosis by activating the immune system by activating interactions with the NK cells. Understanding the molecular regulation of HSteC activation may lead to the development of new therapies for treatment of hepatic fibrosis and chronic liver disease.
Organism species: Homo sapiens (Human)
- Cell CSI071Hu01 Primary Human Hepatic Stellate Cells (HSC) In Stock
- Customized Service n/a Extract of Hepatic Stellate Cells (HSC) Total Protein/DNA/RNA Extract Customized Service Offer
- Customized Service n/a Medium for Hepatic Stellate Cells (HSC) (If Necessary) Cell Culture Medium Customized Service Offer
Organism species: Mus musculus (Mouse)
- Cell CSI071Mu01 Primary Mouse Hepatic Stellate Cells (HSC) In Stock
- Customized Service n/a Extract of Hepatic Stellate Cells (HSC) Total Protein/DNA/RNA Extract Customized Service Offer
- Medium MSI071Mu11 Medium for Mouse Hepatic Stellate Cells (HSC) In Stock
Organism species: Rattus norvegicus (Rat)
- Cell CSI071Ra01 Primary Rat Hepatic Stellate Cells (HSC) In Stock
- Customized Service n/a Extract of Hepatic Stellate Cells (HSC) Total Protein/DNA/RNA Extract Customized Service Offer
- Medium MSI071Ra11 Medium for Rat Hepatic Stellate Cells (HSC) In Stock
Organism species: Oryctolagus cuniculus (Rabbit)
- Cell CSI071Rb01 Primary Rabbit Hepatic Stellate Cells (HSC) In Stock
- Customized Service n/a Extract of Hepatic Stellate Cells (HSC) Total Protein/DNA/RNA Extract Customized Service Offer
- Medium MSI071Rb11 Medium for Rabbit Hepatic Stellate Cells (HSC) In Stock
Organism species: Canis familiaris; Canine (Dog)
- Cell CSI071Ca01 Primary Canine Hepatic Stellate Cells (HSC) In Stock
- Customized Service n/a Extract of Hepatic Stellate Cells (HSC) Total Protein/DNA/RNA Extract Customized Service Offer
- Medium MSI071Ca11 Medium for Canine Hepatic Stellate Cells (HSC) In Stock