Hepatocellular Carcinoma Cells (HCC)

Hepatocellular carcinoma, also called malignant hepatoma, is the most common type of liver cancer. Most cases of HCC are as a result of either a viral hepatitis infection, metabolic toxins such as alcohol or aflatoxin, conditions like hemochromatosis and alpha 1-antitrypsin deficiency or NASH. 

HepG2 is a human hepatocellular carcinoma cells line, which is epithelial in morphology, have a modal chromosome number of 55, and are not tumorigenic in nude mice. The cells secrete a variety of major plasma proteins.They have been grown successfully in large-scale cultivation systems. HepG2 will respond to stimulation with human growth hormone.