Immunoglobulin Binding Protein 1 (IGBP1)

IBP1; B-cell signal transduction molecule alpha 4; CD79a-binding protein 1; Protein phosphatase 2/4/6 regulatory subunit; Renal carcinoma antigen NY-REN-16

Immunoglobulin Binding Protein 1 (IGBP1)
Immunoglobulin-binding protein 1 is a protein encoded by the IGBP1 gene.The proliferation and differentiation of B cells is dependent upon a B-cell antigen receptor (BCR) complex. Binding of antigens to specific B-cell receptors results in a tyrosine phosphorylation reaction through the BCR complex and leads to multiple signal transduction pathways.
Associated to surface IgM-receptor; may be involved in signal transduction. May be involved in regulation of the catalytic activity of type 2A-related serine/threonine phosphatases.Ubiquitously expressed with highest levels in heart, skeletal muscle and pancreas.Defects in IGBP1 are the cause of agenesis of the corpus callosum with mental retardation-ocular coloboma-micrognathia (ACCMRCM)

Organism species: Homo sapiens (Human)

Organism species: Mus musculus (Mouse)

Organism species: Rattus norvegicus (Rat)

Organism species: Bos taurus; Bovine (Cattle)