Interleukin 23 (IL23)
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Interleukin-23 (IL-23) is a heterodimeric cytokine composed of an IL12B (IL-12p40) subunit (that is shared with IL12) and the IL23A (IL-23p19) subunit. A functional receptor for IL-23 (the IL-23 receptor) has been identified and is composed of IL-12R β1 and IL-23R. Prior to the discovery of IL-23, IL-12 had been proposed to represent a key mediator of inflammation in mouse models of inflammation. However, many studies aimed at assessing the role of IL-12 had blocked the activity of IL-12p40, and were therefore not as specific as thought. Studies which blocked the function of IL-12p35 did not produce the same results as those targeting IL-12p40 as would have been expected if both subunits formed part of IL-12 only. The discovery of an additional potential binding partner for IL-12p40 led to a reassessment of this role for IL-12.
Organism species: Homo sapiens (Human)
- Eukaryotic protein EPX262Hu61 Eukaryotic Interleukin 23 (IL23) In Stock
- Eukaryotic protein EPX262Hu62 Eukaryotic Interleukin 23 (IL23) In Stock
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- Customized Service n/a Polyclonal Antibody to Interleukin 23 (IL23) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Interleukin 23 (IL23) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Interleukin 23 (IL23) ELISA Kit Customized Service Offer
Organism species: Mus musculus (Mouse)
- Recombinant protein RPX262Mu01 Recombinant Interleukin 23 (IL23) In Stock
- Eukaryotic protein EPX262Mu61 Eukaryotic Interleukin 23 (IL23) In Stock
- Active protein APX262Mu61 Active Interleukin 23 (IL23) In Stock
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- Customized Service n/a Polyclonal Antibody to Interleukin 23 (IL23) Polyclonal Antibody Customized Service Offer
- Sandwich ELISA SEX262Mu ELISA Kit for Interleukin 23 (IL23) In Stock
Organism species: Bos taurus; Bovine (Cattle)
- Recombinant protein RPX262Bo01 Recombinant Interleukin 23 (IL23) In Stock
- Customized Service n/a Monoclonal Antibody to Interleukin 23 (IL23) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Interleukin 23 (IL23) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Interleukin 23 (IL23) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Interleukin 23 (IL23) ELISA Kit Customized Service Offer