Amylin
IAPP; IAP; DAP; Islet Amyloid Polypeptide; Insulinoma Amyloid Polypeptide; Diabetes-associated peptide
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Islet, or insulinoma, amyloid polypeptide (IAPP, or amylin) is commonly found in pancreatic islets of patients suffering diabetes mellitus type 2, or harboring an insulinoma. While the association of amylin with the development of type 2 diabetes has been known for some time, a direct causative role for amylin has been harder to establish.
Recent results suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in insulin-producing beta cells, an effect that may be relevant to the development of type 2 diabetes. Finally, a recent study reported a synergistic effect for weight loss with leptin and amylin coadministration in diet-induced obese rats by restoring hypothalamic sensitivity to leptin .
Organism species: Homo sapiens (Human)
- Recombinant protein RPA812Hu01 Recombinant Amylin In Stock
- Conjugated small molecules CPA812Hu22 OVA Conjugated Amylin In Stock
- Conjugated small molecules CPA812Hu11 BSA Conjugated Amylin In Stock
- Conjugated small molecules CPA812Hu21 OVA Conjugated Amylin In Stock
- Conjugated small molecules CPA812Hu33 KLH Conjugated Amylin In Stock
- Polyclonal antibody PAA812Hu01 Polyclonal Antibody to Amylin In Stock
- Monoclonal antibody MAA812Hu22 Monoclonal Antibody to Amylin In Stock
- Polyclonal antibody PAA812Hu07 Polyclonal Antibody to Amylin In Stock
- Polyclonal antibody PAA812Hu08 Polyclonal Antibody to Amylin In Stock
- Monoclonal antibody MAA812Mi28 Monoclonal Antibody to Amylin In Stock
- Competition ELISA CEA812Hu ELISA Kit for Amylin In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPA812Mu01 Recombinant Amylin In Stock
- Recombinant protein RPA812Mu02 Recombinant Amylin In Stock
- Conjugated small molecules CPA812Mu11 BSA Conjugated Amylin In Stock
- Conjugated small molecules CPA812Mu21 OVA Conjugated Amylin In Stock
- Polyclonal antibody PAA812Mu01 Polyclonal Antibody to Amylin In Stock
- Polyclonal antibody PAA812Mu02 Polyclonal Antibody to Amylin In Stock
- Polyclonal antibody PAA812Mu08 Polyclonal Antibody to Amylin In Stock
- Competition ELISA CEA812Mu ELISA Kit for Amylin In Stock
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPA812Ra01 Recombinant Amylin In Stock
- Conjugated small molecules CPA812Ra11 BSA Conjugated Amylin In Stock
- Conjugated small molecules CPA812Ra21 OVA Conjugated Amylin In Stock
- Polyclonal antibody PAA812Ra01 Polyclonal Antibody to Amylin In Stock
- Monoclonal antibody MAA812Ra21 Monoclonal Antibody to Amylin In Stock
- Polyclonal antibody PAA812Ra08 Polyclonal Antibody to Amylin In Stock
- Competition ELISA CEA812Ra ELISA Kit for Amylin In Stock
Organism species: Pan-species (General)
- Customized Service n/a Recombinant Amylin Recombinant Protein Customized Service Offer
- Monoclonal antibody MAA812Ge21 Monoclonal Antibody to Amylin In Stock
- Monoclonal antibody MAA812Ge28 Monoclonal Antibody to Amylin In Stock
- Customized Service n/a CLIA Kit for Amylin CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Amylin ELISA Kit Customized Service Offer