Lens Intrinsic Membrane Protein 2 (LIM2)
MP19; Lens Fiber Membrane Intrinsic Protein
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The mammalian lens fiber cell membrane contains 5 major proteins ranging from 70 kD to 19 kD in size. The specific function of these proteins is unknown. Some of them have been shown to be involved in the formation of cataracts, e.g., crystalline-gamma-1 (CRYG1). The second most abundant intrinsic membrane protein of the lens fiber cell is MP19, so named for major lens protein having a molecular weight of 19.5 kD. This protein appears to contain 4 transmembrane domains, is a substrate for cAMP-dependent protein kinase and protein kinase C, and binds with calmodulin. Taken together, these suggest that MP19 functions in some way as a junctional component, possibly involved with lens cell communication. It has been shown to be involved with cataractogenesis.
Organism species: Homo sapiens (Human)
- Recombinant protein RPC566Hu01 Recombinant Lens Intrinsic Membrane Protein 2 (LIM2) In Stock
- Polyclonal antibody PAC566Hu01 Polyclonal Antibody to Lens Intrinsic Membrane Protein 2 (LIM2) In Stock
- Customized Service n/a CLIA Kit for Lens Intrinsic Membrane Protein 2 (LIM2) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Lens Intrinsic Membrane Protein 2 (LIM2) ELISA Kit Customized Service Offer
Organism species: Mus musculus (Mouse)
- Recombinant protein RPC566Mu01 Recombinant Lens Intrinsic Membrane Protein 2 (LIM2) In Stock
- Polyclonal antibody PAC566Mu01 Polyclonal Antibody to Lens Intrinsic Membrane Protein 2 (LIM2) In Stock
- Customized Service n/a CLIA Kit for Lens Intrinsic Membrane Protein 2 (LIM2) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Lens Intrinsic Membrane Protein 2 (LIM2) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Lens Intrinsic Membrane Protein 2 (LIM2) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Lens Intrinsic Membrane Protein 2 (LIM2) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Lens Intrinsic Membrane Protein 2 (LIM2) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Lens Intrinsic Membrane Protein 2 (LIM2) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Lens Intrinsic Membrane Protein 2 (LIM2) ELISA Kit Customized Service Offer