Low Density Lipoprotein Receptor Related Protein 1 (LRP1)
CD91; LRP; A2MR; APOER; APR; TGFBR5; Alpha-2-Macroglobulin Receptor; Prolow-density lipoprotein receptor-related protein 1; Apolipoprotein E receptor
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Low density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor), also known as LRP1 or CD91, is a protein forming a receptor found in the plasma membrane of human cells involved in receptor-mediated endocytosis.Neurons require cholesterol to function. Cholesterol is imported into the neuron by the apolipoprotein apoE4 via LRP1 receptors on the cell surface. It is thought that a causal factor in Alzheimer's is the malfunction of this process which damages neurons by starving them of cholesterol.The protein showed strong calcium binding. Kristensen et al. (1990) and Strickland et al. (1990) demonstrated that LRP is identical to the alpha-2-macroglobulin (A2M) receptor (A2MR). Like the mannose-6-phosphate receptor, the A2MR/LRP molecule is probably bifunctional.
Organism species: Homo sapiens (Human)
- Recombinant protein RPB010Hu01 Recombinant Low Density Lipoprotein Receptor Related Protein 1 (LRP1) In Stock
- Recombinant protein RPB010Hu02 Recombinant Low Density Lipoprotein Receptor Related Protein 1 (LRP1) In Stock
- Polyclonal antibody PAB010Hu01 Polyclonal Antibody to Low Density Lipoprotein Receptor Related Protein 1 (LRP1) In Stock
- Monoclonal antibody MAB010Hu22 Monoclonal Antibody to Low Density Lipoprotein Receptor Related Protein 1 (LRP1) In Stock
- Monoclonal antibody MAB010Hu21 Monoclonal Antibody to Low Density Lipoprotein Receptor Related Protein 1 (LRP1) In Stock
- Monoclonal antibody MAB010Hu23 Monoclonal Antibody to Low Density Lipoprotein Receptor Related Protein 1 (LRP1) In Stock
- Monoclonal antibody MAB010Hu24 Monoclonal Antibody to Low Density Lipoprotein Receptor Related Protein 1 (LRP1) In Stock
- Sandwich ELISA SEB010Hu ELISA Kit for Low Density Lipoprotein Receptor Related Protein 1 (LRP1) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPB010Mu01 Recombinant Low Density Lipoprotein Receptor Related Protein 1 (LRP1) In Stock
- Recombinant protein RPB010Mu02 Recombinant Low Density Lipoprotein Receptor Related Protein 1 (LRP1) In Stock
- Polyclonal antibody PAB010Mu01 Polyclonal Antibody to Low Density Lipoprotein Receptor Related Protein 1 (LRP1) In Stock
- Polyclonal antibody PAB010Mu02 Polyclonal Antibody to Low Density Lipoprotein Receptor Related Protein 1 (LRP1) In Stock
- Sandwich ELISA SEB010Mu ELISA Kit for Low Density Lipoprotein Receptor Related Protein 1 (LRP1) In Stock
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Low Density Lipoprotein Receptor Related Protein 1 (LRP1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Low Density Lipoprotein Receptor Related Protein 1 (LRP1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Low Density Lipoprotein Receptor Related Protein 1 (LRP1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Low Density Lipoprotein Receptor Related Protein 1 (LRP1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Low Density Lipoprotein Receptor Related Protein 1 (LRP1) ELISA Kit Customized Service Offer