Lymphotoxin Beta Receptor (LTbR)
TNFCR; TNFR-RP; TNFR-III; TNFR2-RP; TNFRSF3; Tumor Necrosis Factor Superfamily Member 3; Tumor necrosis factor C receptor; Tumor necrosis factor receptor type III
LTBR is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and transformed cells. Activation of the encoded protein can trigger apoptosis.Not only does the LTBR help trigger apoptosis, it can lead to the release of the cytokine interleukin 8. Overexpression of LTBR in HEK293 cells increases IL-8 promoter activity and leads to IL-8 release. LTBR is also essential for development and organization of the secondary lymphoid organs and chemokine release.
Organism species: Homo sapiens (Human)
- Recombinant protein RPA481Hu01 Recombinant Lymphotoxin Beta Receptor (LTbR) In Stock
- Recombinant protein RPA481Hu02 Recombinant Lymphotoxin Beta Receptor (LTbR) In Stock
- Polyclonal antibody PAA481Hu01 Polyclonal Antibody to Lymphotoxin Beta Receptor (LTbR) In Stock
- Labelled antibody LAA481Hu71 Biotin-Linked Polyclonal Antibody to Lymphotoxin Beta Receptor (LTbR) In Stock
- Monoclonal antibody MAA481Hu21 Monoclonal Antibody to Lymphotoxin Beta Receptor (LTbR) In Stock
- Monoclonal antibody MAA481Hu22 Monoclonal Antibody to Lymphotoxin Beta Receptor (LTbR) In Stock
- Sandwich ELISA SEA481Hu ELISA Kit for Lymphotoxin Beta Receptor (LTbR) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPA481Mu01 Recombinant Lymphotoxin Beta Receptor (LTbR) In Stock
- Recombinant protein RPA481Mu02 Recombinant Lymphotoxin Beta Receptor (LTbR) In Stock
- Polyclonal antibody PAA481Mu01 Polyclonal Antibody to Lymphotoxin Beta Receptor (LTbR) In Stock
- Customized Service n/a CLIA Kit for Lymphotoxin Beta Receptor (LTbR) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Lymphotoxin Beta Receptor (LTbR) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Lymphotoxin Beta Receptor (LTbR) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Lymphotoxin Beta Receptor (LTbR) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Lymphotoxin Beta Receptor (LTbR) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Lymphotoxin Beta Receptor (LTbR) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Lymphotoxin Beta Receptor (LTbR) ELISA Kit Customized Service Offer