Lysosomal Associated Membrane Protein 1 (LAMP1)

Lysosomal-associated membrane protein 1 (LAMP1) also known as CD107a (Cluster of Differentiation 107a) , The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis.

The deduced amino acid sequence demonstrated that the rat LGP120 contains a putative signal peptide, 18 sites for N-linked glycosylation, a single membrane-spanning segment, and a short (11 amino acid) cytosolic tail. LGP120 showed similarity to 2 other lysosomal membrane proteins and showed a high degree of conservation in domain organization and primary structure with the proteins in other species.