Methylenetetrahydrofolate Reductase (MTHFR)
5,10-Methylenetetrahydrofolate Reductase(NADPH)
Methylenetetrahydrofolate reductase (EC 1.5.1.20) catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a cosubstrate for homocysteine remethylation to methionine.
Sequence data from the porcine DNA were then used to screen a human liver cDNA library by PCR for isolation of a partial human cDNA, the predicted amino acid sequence of which showed strong homology to porcine MTHFR and to bacterial metF genes. The encoded 656-amino acid protein is a homodimer with a total molecular mass of 150 kD. The human and mouse MTHFR proteins share approximately 90% identity.The different sized transcripts resulted from alternate transcription start sites and polyadenylation signals.
Organism species: Homo sapiens (Human)
- Recombinant protein RPH609Hu01 Recombinant Methylenetetrahydrofolate Reductase (MTHFR) In Stock
- Polyclonal antibody PAH609Hu01 Polyclonal Antibody to Methylenetetrahydrofolate Reductase (MTHFR) In Stock
- Monoclonal antibody MAH609Hu21 Monoclonal Antibody to Methylenetetrahydrofolate Reductase (MTHFR) In Stock
- Sandwich ELISA SEH609Hu ELISA Kit for Methylenetetrahydrofolate Reductase (MTHFR) In Stock
Organism species: Mus musculus (Mouse)
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- Sandwich ELISA SEH609Mu ELISA Kit for Methylenetetrahydrofolate Reductase (MTHFR) In Stock
Organism species: Rattus norvegicus (Rat)
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- Customized Service n/a Monoclonal Antibody to Methylenetetrahydrofolate Reductase (MTHFR) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Methylenetetrahydrofolate Reductase (MTHFR) Polyclonal Antibody Customized Service Offer
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