Nephroblastoma Cells (NBC)

Wilms tumor, also known as nephroblastoma, is a cancer of the kidneys that typically occurs in children, rarely in adults. Wilms tumor is a malignant tumor containing metanephric blastema, stromal and epithelial derivatives. Characteristic is the presence of abortive tubules and glomeruli surrounded by a spindled cell stroma. The stroma may include striated muscle, cartilage, bone, fat tissue, fibrous tissue. Dysfunction is caused when the tumor compresses the normal kidney parenchyma. SK-NEP-1 cell line is the commonly used nephroblastoma cells derived from human.