Nuclear Receptor Related Protein 1 (NURR1)
NR4A2; RNR1; HZF-3; NOT; TINUR; Nuclear Receptor Subfamily 4,Group A,Member 2; Transcriptionally-inducible nuclear receptor; Immediate-early response protein NOT
NURR1 plays a key role in the maintenance of the dopaminergic system of the brain. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson's disease, schizophrenia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Four transcript variants encoding four distinct isoforms have been identified for this gene. Additional alternate splice variants may exist, but their full length nature has not been determined.
A human T-lymphoid cell line, PEER, dies by apoptosis in the presence of phorbol myristate acetate (PMA) and calcium ionophore. The gene encodes a 535-amino acid protein that belongs to the NGFIB/nur77 steroid receptor family.
Organism species: Homo sapiens (Human)
- Recombinant protein RPD964Mi01 Recombinant Nuclear Receptor Related Protein 1 (NURR1) In Stock
- Recombinant protein RPD964Hu01 Recombinant Nuclear Receptor Related Protein 1 (NURR1) In Stock
- Recombinant protein RPD964Hu02 Recombinant Nuclear Receptor Related Protein 1 (NURR1) In Stock
- Polyclonal antibody PAD964Mi01 Polyclonal Antibody to Nuclear Receptor Related Protein 1 (NURR1) In Stock
- Polyclonal antibody PAD964Hu01 Polyclonal Antibody to Nuclear Receptor Related Protein 1 (NURR1) In Stock
- Sandwich ELISA SED964Mi ELISA Kit for Nuclear Receptor Related Protein 1 (NURR1) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPD964Mi01 Recombinant Nuclear Receptor Related Protein 1 (NURR1) In Stock
- Polyclonal antibody PAD964Mi01 Polyclonal Antibody to Nuclear Receptor Related Protein 1 (NURR1) In Stock
- Sandwich ELISA SED964Mi ELISA Kit for Nuclear Receptor Related Protein 1 (NURR1) In Stock
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPD964Mi01 Recombinant Nuclear Receptor Related Protein 1 (NURR1) In Stock
- Polyclonal antibody PAD964Mi01 Polyclonal Antibody to Nuclear Receptor Related Protein 1 (NURR1) In Stock
- Sandwich ELISA SED964Mi ELISA Kit for Nuclear Receptor Related Protein 1 (NURR1) In Stock