Osteonectin (ON)
SPARC; BM-40; Secreted Protein,Acidic,Cysteine-Rich; Basement-membrane protein 40; Secreted protein acidic and rich in cysteine
Osteonectin is a glycoprotein in the bone that binds calcium. It is secreted by osteoblasts during bone formation, initiating mineralization and promoting mineral crystal formation. Osteonectin also shows affinity for collagen in addition to bone mineral calcium. Some current research shows a correlation between osteonectin over expression and ampullary cancers and chronic pancreatitis. Osteonectin is an acidic, secreted extracellular matrix glycoprotein that plays a vital role in bone mineralization, cell-matrix interactions, and collagen binding. Osteonectin also increases the production and activity of matrix metalloproteinases, a function important to invading cancer cells within bone. Additional functions of osteonectin beneficial to tumor cells include angiogenesis, proliferation and migration.
Organism species: Homo sapiens (Human)
- Recombinant protein RPA791Hu01 Recombinant Osteonectin (ON) In Stock
- Conjugated small molecules CPA791Hu21 OVA Conjugated Osteonectin (ON) In Stock
- Active protein APA791Hu01 Active Osteonectin (ON) In Stock
- Eukaryotic protein EPA791Hu61 Eukaryotic Osteonectin (ON) In Stock
- Active protein APA791Hu61 Active Osteonectin (ON) In Stock
- Monoclonal antibody MAA791Hu22 Monoclonal Antibody to Osteonectin (ON) In Stock
- Labelled antibody LAA791Hu71 Biotin-Linked Polyclonal Antibody to Osteonectin (ON) In Stock
- Labelled antibody LAA791Hu81 FITC-Linked Polyclonal Antibody to Osteonectin (ON) In Stock
- Polyclonal antibody PAA791Hu01 Polyclonal Antibody to Osteonectin (ON) In Stock
- Polyclonal antibody PAA791Hu08 Polyclonal Antibody to Osteonectin (ON) In Stock
- Sandwich ELISA SEA791Hu ELISA Kit for Osteonectin (ON) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPA791Mu01 Recombinant Osteonectin (ON) In Stock
- Recombinant protein RPA791Mu02 Recombinant Osteonectin (ON) In Stock
- Polyclonal antibody PAA791Mu01 Polyclonal Antibody to Osteonectin (ON) In Stock
- Labelled antibody LAA791Mu71 Biotin-Linked Polyclonal Antibody to Osteonectin (ON) In Stock
- Labelled antibody LAA791Mu81 FITC-Linked Polyclonal Antibody to Osteonectin (ON) In Stock
- Polyclonal antibody PAA791Mu02 Polyclonal Antibody to Osteonectin (ON) In Stock
- Sandwich ELISA SEA791Mu ELISA Kit for Osteonectin (ON) In Stock
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPA791Ra01 Recombinant Osteonectin (ON) In Stock
- Polyclonal antibody PAA791Ra01 Polyclonal Antibody to Osteonectin (ON) In Stock
- Labelled antibody LAA791Ra71 Biotin-Linked Polyclonal Antibody to Osteonectin (ON) In Stock
- Labelled antibody LAA791Ra81 FITC-Linked Polyclonal Antibody to Osteonectin (ON) In Stock
- Monoclonal antibody MAA791Ra21 Monoclonal Antibody to Osteonectin (ON) In Stock
- Sandwich ELISA SEA791Ra ELISA Kit for Osteonectin (ON) In Stock
Organism species: Oryctolagus cuniculus (Rabbit)
- Recombinant protein RPA791Rb01 Recombinant Osteonectin (ON) In Stock
- Polyclonal antibody PAA791Rb51 Polyclonal Antibody to Osteonectin (ON) In Stock
- Polyclonal antibody PAA791Rb01 Polyclonal Antibody to Osteonectin (ON) In Stock
- Customized Service n/a CLIA Kit for Osteonectin (ON) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Osteonectin (ON) ELISA Kit Customized Service Offer
Organism species: Sus scrofa; Porcine (Pig)
- Customized Service n/a Recombinant Osteonectin (ON) Recombinant Protein Customized Service Offer
- Polyclonal antibody PAA791Po01 Polyclonal Antibody to Osteonectin (ON) In Stock
- Customized Service n/a CLIA Kit for Osteonectin (ON) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Osteonectin (ON) ELISA Kit Customized Service Offer