Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1)
BDGI; OKL38; Bone Marrow Stromal Cell-Derived Growth Inhibitor; Pregnancy Induced Growth Inhibitor; Ovary, kidney and liver protein 38
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The deduced 317-amino acid protein has a calculated molecular mass of about 34.5 kD. OKL38 does not have a transmembrane domain or signal peptide. Minor transcripts of 3.6 and 4.0 kb were also observed.
In situ hybridization detected Okl38 in undifferentiated mammary epithelial cells of nonpregnant rats, and expression was upregulated in secretory epithelial of 18-day pregnant rats. Northern blot analysis detected reduced OKL38 expression in human breast cancer cell lines compared with normal mammary tissue. Expression was also reduced in chemically-induced rat mammary tumors. Overexpression of OKL38 in a human breast cancer cell line reduced the ability of these cells to form tumors in nude mice.
Organism species: Homo sapiens (Human)
- Recombinant protein RPG202Hu01 Recombinant Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) In Stock
- Monoclonal antibody MAG202Hu21 Monoclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) In Stock
- Polyclonal antibody PAG202Hu01 Polyclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) In Stock
- Sandwich ELISA SEG202Hu ELISA Kit for Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) In Stock
Organism species: Mus musculus (Mouse)
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Organism species: Rattus norvegicus (Rat)
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