Oxysterol Binding Protein Like Protein 8 (OSBPL8)
ORP8; OSBP10; Oxysterol-Binding Protein-Related Protein 8
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OSBPL8 is a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Two transcript variants encoding different isoforms have been found for this gene.The deduced 488-amino acid protein was predicted to be 33% identical to mouse Osbp. RT-PCR analysis detected wide expression that was strongest in testis, ovary, liver, kidney, and brain. Within brain, expression was particularly strong in caudate nucleus.Sequence analysis predicted that the 847-amino acid protein contains a C-terminal sterol-binding (SB) domain of approximately 400 residues that includes the OSBP motif (EQVSHHPP).
Organism species: Homo sapiens (Human)
- Recombinant protein RPF701Hu01 Recombinant Oxysterol Binding Protein Like Protein 8 (OSBPL8) In Stock
- Monoclonal antibody MAF701Hu21 Monoclonal Antibody to Oxysterol Binding Protein Like Protein 8 (OSBPL8) In Stock
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Organism species: Mus musculus (Mouse)
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Organism species: Rattus norvegicus (Rat)
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