Paired Like Homeobox Protein 2A (PHOX2A)
ARIX; CFEOM2; FEOM2; NCAM2; PMX2A; ARIX1 homeodomain protein; Aristaless Homeobox Fibrosis Of Extraocular Muscles Congenital 2 Autosomal Recessive
-98996.jpg)
PHOX2A encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype.
The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles.
Organism species: Homo sapiens (Human)
- Customized Service n/a Recombinant Paired Like Homeobox Protein 2A (PHOX2A) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Paired Like Homeobox Protein 2A (PHOX2A) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Paired Like Homeobox Protein 2A (PHOX2A) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Paired Like Homeobox Protein 2A (PHOX2A) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Paired Like Homeobox Protein 2A (PHOX2A) ELISA Kit Customized Service Offer
Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant Paired Like Homeobox Protein 2A (PHOX2A) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Paired Like Homeobox Protein 2A (PHOX2A) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Paired Like Homeobox Protein 2A (PHOX2A) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Paired Like Homeobox Protein 2A (PHOX2A) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Paired Like Homeobox Protein 2A (PHOX2A) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Paired Like Homeobox Protein 2A (PHOX2A) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Paired Like Homeobox Protein 2A (PHOX2A) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Paired Like Homeobox Protein 2A (PHOX2A) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Paired Like Homeobox Protein 2A (PHOX2A) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Paired Like Homeobox Protein 2A (PHOX2A) ELISA Kit Customized Service Offer