Phosphatidic Acid Phosphatase Type 2C (PPAP2C)

PPAP2-C; LPP2; PAP-2c; PAP2-g; Lipid phosphate phosphohydrolase 2; Phosphatidate phosphohydrolase type 2c

Phosphatidic Acid Phosphatase Type 2C (PPAP2C)
Lipid phosphate phosphohydrolase 2 is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D.
This protein is similar to phosphatidic acid phosphatase type 2A (PPAP2A) and type 2B (PPAP2B). All three proteins contain 6 transmembrane regions, and a consensus N-glycosylation site.
Phosphatidic Acid Phosphatase Type 2C has been shown to possess membrane associated PAP activity. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.

Organism species: Homo sapiens (Human)

Organism species: Mus musculus (Mouse)

Organism species: Rattus norvegicus (Rat)