Phospholipase C Gamma 1 (PLCg1)
NCKAP3; PLC-G1; PLC-II; PLC1; PLC148; PLCgamma1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; Phosphoinositide phospholipase C-gamma-1
Phospholipase C, gamma 1 catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase.
Researchers studying PLCg1 and its role in breast cancer metastasis discovered this gene can promote cancer metastasis and subsequently blocking it stopped cancer from spreading. Research is ongoing but this gene could lead to the development of new anti-cancer drugs.
Organism species: Homo sapiens (Human)
- Recombinant protein RPA269Hu01 Recombinant Phospholipase C Gamma 1 (PLCg1) In Stock
- Polyclonal antibody PAA269Hu01 Polyclonal Antibody to Phospholipase C Gamma 1 (PLCg1) In Stock
- Monoclonal antibody MAA269Hu22 Monoclonal Antibody to Phospholipase C Gamma 1 (PLCg1) In Stock
- Sandwich ELISA SEA269Hu ELISA Kit for Phospholipase C Gamma 1 (PLCg1) In Stock
Organism species: Mus musculus (Mouse)
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Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Phospholipase C Gamma 1 (PLCg1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Phospholipase C Gamma 1 (PLCg1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Phospholipase C Gamma 1 (PLCg1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Phospholipase C Gamma 1 (PLCg1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Phospholipase C Gamma 1 (PLCg1) ELISA Kit Customized Service Offer