Pronociceptin (PNOC)
PPNOC; Prepronociceptin; Pocistatin; Pro-nociceptin; Preproorphanin FQ; Neuropeptide 1; Nociceptin; Orphanin FQ
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Nociceptin (orphanin FQ), a neuropeptide of 17 amino acids, is the natural agonist of opioid receptor-like-1 (OPRL1), a G protein-coupled receptor whose human and murine cDNAs had previously been identified. This neuropeptide is endowed with pronociceptive activity in vivo. Nociceptin is derived from a larger precursor, prepronociceptin (PNOC) is highly conserved in the 3 species and displays organizational features that are strikingly similar to those for the genes for preproenkephalin, preprodynorphin, and preproopiomelanocortin. Mollereau et al. showed that the PNOC gene encodes a single copy of nociceptin as well as another peptide whose sequence is strictly conserved across murine and human species; hence, it is likely to be neurophysiologically significant.
Organism species: Homo sapiens (Human)
- Recombinant protein RPD397Hu01 Recombinant Pronociceptin (PNOC) In Stock
- Conjugated small molecules CPD397Hu21 OVA Conjugated Pronociceptin (PNOC) In Stock
- Polyclonal antibody PAD397Hu01 Polyclonal Antibody to Pronociceptin (PNOC) In Stock
- Labelled antibody LAD397Hu71 Biotin-Linked Polyclonal Antibody to Pronociceptin (PNOC) In Stock
- Monoclonal antibody MAD397Hu21 Monoclonal Antibody to Pronociceptin (PNOC) In Stock
- Sandwich ELISA SED397Hu ELISA Kit for Pronociceptin (PNOC) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPD397Mu01 Recombinant Pronociceptin (PNOC) In Stock
- Conjugated small molecules CPD397Mu21 OVA Conjugated Pronociceptin (PNOC) In Stock
- Polyclonal antibody PAD397Mu01 Polyclonal Antibody to Pronociceptin (PNOC) In Stock
- Customized Service n/a CLIA Kit for Pronociceptin (PNOC) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Pronociceptin (PNOC) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPD397Ra01 Recombinant Pronociceptin (PNOC) In Stock
- Conjugated small molecules CPD397Ra21 OVA Conjugated Pronociceptin (PNOC) In Stock
- Polyclonal antibody PAD397Ra01 Polyclonal Antibody to Pronociceptin (PNOC) In Stock
- Customized Service n/a CLIA Kit for Pronociceptin (PNOC) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Pronociceptin (PNOC) ELISA Kit Customized Service Offer