Prostaglandin-H2 D-isomerase (PTGDS)
PGD2S; PDS; PGDS2; Prostaglandin D2 Synthase, Brain; Lipocalin-Type Prostaglandin D Synthase; Cerebrin-28; Beta-trace protein; Glutathione-independent PGD synthase
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PTGDS is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to prostaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice over-expressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. Furthermore, PTGDS and its product PGD2 are elevated in the bald-scalp areas of men with male pattern baldness. Prostaglandin D2 synthase is used clinically as a diagnostic marker for liquorrhea, that is, to check whether fluid leaking from the nose or ear contains cerebrospinal fluid.
Organism species: Homo sapiens (Human)
- Recombinant protein RPA724Hu01 Recombinant Prostaglandin-H2 D-isomerase (PTGDS) In Stock
- Polyclonal antibody PAA724Hu01 Polyclonal Antibody to Prostaglandin-H2 D-isomerase (PTGDS) In Stock
- Monoclonal antibody MAA724Hu22 Monoclonal Antibody to Prostaglandin-H2 D-isomerase (PTGDS) In Stock
- Monoclonal antibody MAA724Hu21 Monoclonal Antibody to Prostaglandin-H2 D-isomerase (PTGDS) In Stock
- Monoclonal antibody MAA724Hu23 Monoclonal Antibody to Prostaglandin-H2 D-isomerase (PTGDS) In Stock
- Monoclonal antibody MAA724Hu24 Monoclonal Antibody to Prostaglandin-H2 D-isomerase (PTGDS) In Stock
- Labelled antibody LAA724Hu74 Biotin-Linked Monoclonal Antibody to Prostaglandin-H2 D-isomerase (PTGDS) In Stock
- Sandwich ELISA SEA724Hu ELISA Kit for Prostaglandin-H2 D-isomerase (PTGDS) In Stock
Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant Prostaglandin-H2 D-isomerase (PTGDS) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Prostaglandin-H2 D-isomerase (PTGDS) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Prostaglandin-H2 D-isomerase (PTGDS) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Prostaglandin-H2 D-isomerase (PTGDS) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Prostaglandin-H2 D-isomerase (PTGDS) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Prostaglandin-H2 D-isomerase (PTGDS) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Prostaglandin-H2 D-isomerase (PTGDS) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Prostaglandin-H2 D-isomerase (PTGDS) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Prostaglandin-H2 D-isomerase (PTGDS) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Prostaglandin-H2 D-isomerase (PTGDS) ELISA Kit Customized Service Offer