Proteasome Subunit Alpha Type 6 (PSMa6)
IOTA; PROS27; p27K; 27 kDa prosomal protein; Macropain iota chain; Proteasome iota chain; Multicatalytic endopeptidase complex iota chain
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.
Proteasome Subunit Alpha Type 6 is a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome.
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
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Organism species: Rattus norvegicus (Rat)
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- Customized Service n/a Monoclonal Antibody to Proteasome Subunit Alpha Type 6 (PSMa6) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Proteasome Subunit Alpha Type 6 (PSMa6) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Proteasome Subunit Alpha Type 6 (PSMa6) CLIA Kit Customized Service Offer
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