Protein Tyrosine Phosphatase, Non Receptor Type 14 (PTPN14)

Tyrosine-protein phosphatase non-receptor type 14 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.

This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. The specific function of this PTP has not yet been determined.Expressed in a variety of human tissues including kidney, skeletal muscle, lung and placenta.