Purinergic Receptor P2Y, G Protein Coupled 14 (P2RY14)

P2Y purinoceptor 14 is a protein belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides.

This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene.The predicted 338-amino acid protein contains transmembrane domains and a tyrosine kinase phosphorylation site.