Pyruvate dehydrogenase alpha 1 (PDHA1)
PDHCE1A; PHE1A; PHE1-A; PDHa; PDH-A; Pyruvate Dehydrogenase(lipoamide)Alpha 1; Pyruvate Dehydrogenase E1 Component Subunit Alpha,Aomatic Form,Mitochondrial; Pyruvate Dehydrogenase Alpha
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The pyruvate dehydrogenase complex is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA. The PDH complex is composed of multiple copies of 3 enzymes: E1 (PDHA1); dihydrolipoyl transacetylase (DLAT) (E2); and dihydrolipoyl dehydrogenase (DLD) (E3). The E1 enzyme is a heterotetramer of 2 alpha and 2 beta subunits. The E1-alpha subunit contains the E1 active site and plays a key role in the function of the PDH complex .Pyruvate dehydrogenase (E1) performs the first two reactions within the pyruvate dehydrogenase complex (PDC): a decarboxylation of substrate 1 (pyruvate) and a reductive acetylation of substrate 2 (lipoic acid).
Organism species: Homo sapiens (Human)
- Recombinant protein RPA776Hu01 Recombinant Pyruvate dehydrogenase alpha 1 (PDHA1) In Stock
- Polyclonal antibody PAA776Hu01 Polyclonal Antibody to Pyruvate dehydrogenase alpha 1 (PDHA1) In Stock
- Monoclonal antibody MAA776Hu22 Monoclonal Antibody to Pyruvate dehydrogenase alpha 1 (PDHA1) In Stock
- Sandwich ELISA SEA776Hu ELISA Kit for Pyruvate dehydrogenase alpha 1 (PDHA1) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPA776Mu01 Recombinant Pyruvate dehydrogenase alpha 1 (PDHA1) In Stock
- Recombinant protein RPA776Mu02 Recombinant Pyruvate dehydrogenase alpha 1 (PDHA1) In Stock
- Polyclonal antibody PAA776Mu01 Polyclonal Antibody to Pyruvate dehydrogenase alpha 1 (PDHA1) In Stock
- Polyclonal antibody PAA776Mu02 Polyclonal Antibody to Pyruvate dehydrogenase alpha 1 (PDHA1) In Stock
- Sandwich ELISA SEA776Mu ELISA Kit for Pyruvate dehydrogenase alpha 1 (PDHA1) In Stock
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPA776Ra01 Recombinant Pyruvate dehydrogenase alpha 1 (PDHA1) In Stock
- Polyclonal antibody PAA776Ra01 Polyclonal Antibody to Pyruvate dehydrogenase alpha 1 (PDHA1) In Stock
- Monoclonal antibody MAA776Ra21 Monoclonal Antibody to Pyruvate dehydrogenase alpha 1 (PDHA1) In Stock
- Sandwich ELISA SEA776Ra ELISA Kit for Pyruvate dehydrogenase alpha 1 (PDHA1) In Stock